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European Platform on Life Cycle Assessment

Zero Pollution publications

  • Page | Last updated: 29 May 2026

Zero Pollution publications

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Purpose. The EU Environmental Footprint (EF) is a life cycle assessment – based method which aims at assessing the environmental impacts of products and organizations through 16 midpoint impact categories, among which three address toxicity-related impacts. This paper presents the principles underpinning the calculation of the set of Characterisation Factors (CFs) for the toxicity-related impact categories in the EF version 3.0: freshwater ecotoxicity (ECOTOX), human toxicity – cancer (HTOX_c) and human toxicity – non-cancer (HTOX_nc). Methods. In order to respond to the issues emerged during the EF pilot phase, the input data and the calculation principles of the USEtox® model were updated. In particular: (i) Robustness Factors (RFs) were introduced to reduce the dominance of metals and to balance the inappropriate modelling of non-organic compounds in USEtox®; (ii) high quality data were selected from databases of EU agencies (European Chemicals Agency and European Food Safety Authority) to guarantee the reliability of input data; and (iii) a new approach based on HC20 (Hazard Concentration killing 20% of the exposed population) was implemented to derive freshwater ecotoxicity Effect Factors (EfF). Results and discussion.
  • Date released: 23 Iul 2022
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The scientific consensus model USEtox® is recommended by the European Commission as the reference model to characterize life cycle chemical emissions in terms of their potential human toxicity and freshwater aquatic ecotoxicity impacts in the context of the International Reference Life Cycle Data System Handbook and the Environmental Footprint pilot phase looking at products (PEF) and organizations (OEF).
  • Date released: 15 June 2017
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