Cardiovascular disease

• 'Available data on the relationship between cholesterol intake and risk of cardiovascular disease are inconsistent at current levels of intake'.

Coronary heart disease

• Possible evidence of 'no association between cholesterol intake and CHD risk in healthy people'.

• 'Much evidence indicates a positive linear trend between cholesterol intake and LDL cholesterol concentration, and therefore an increased risk of CHD'.

Serum lipids

• 'Although there is a positive dose-dependent relationship between the intake of dietary cholesterol with blood LDL cholesterol concentrations, the main dietary determinant of blood LDL cholesterol concentrations is saturated fat intake'.

• 'The evidence is convincing that dietary cholesterol slightly raises the total and LDL cholesterol concentration in plasma. It is conceivable, however, that this effect is considerably higher among the so-called responders or high absorbers'.
• There is probable evidence for 1) an increase of total to HDL cholesterol ratio due to dietary cholesterol, and 2) a lack of association between dietary cholesterol and triglyceride and HDL concentration in plasma.
• 'Insufficient evidence for an association between dietary cholesterol and the ratio of LDL to HDL cholesterol.

• 'There is insufficient evidence to determine whether lowering dietary cholesterol reduced LDL cholesterol'.

• 'Much evidence indicates a positive linear trend between cholesterol intake and LDL cholesterol concentration'.

Stroke

• 'probable evidence that cholesterol intake does not influence the risk of stroke'.

• 'Epidemiological prospective cohort studies have not found consistent relationships between […] cholesterol with the risk to develop type 2 diabetes mellitus'.

• 'No consistent significant associations have been established between dietary cholesterol intake and cancer, including lung, breast, colon, and prostate cancers'.