Skip to main content
Knowledge4Policy
Knowledge for policy

Health Promotion and Disease Prevention Knowledge Gateway

A reference point for public health policy makers with reliable, independent and up-to date information on topics related to promotion of health and well-being.

  • Page | Last updated: 08 Apr 2021

Risk factors related to type 2 diabetes

Risk factors related to type 2 diabetes as described by health-related organisations

Effect of excess adiposity 

WHO 2016 (pdf)
  • 'Excess body fat, a summary measure of several aspects of diet and physical activity, is the strongest risk factor for type 2 diabetes, both in terms of clearest evidence base and largest relative risk.'
IDF 2019
  • 'there is a strong link [for type 2 diabetes] with overweight and obesity'

Effect of diet 

Effect of dietary patterns on type 2 diabetes

ANSES 2016a (pdf)
  • 'Western-type diets, characterised mainly by high intakes of red meat and processed meat (for example delicatessen meats), potato and refined cereal products, full-fat dairy products and butter, and poor in fruits and vegetables, pulses, wholegrain cereal products and fish, increase the risk of type 2 diabetes with a probable level of evidence.'
DGAC 2015
  • 'Moderate evidence indicates that healthy dietary patterns higher in vegetables, fruits, and whole grains and lower in red and processed meats, high-fat dairy products, refined grains, and sweets/sugar-sweetened beverages reduce the risk of developing type 2 diabetes.'
Health Council of the Netherlands 2015
  • Dietary patterns, such as the traditional Mediterranean dietary pattern, the New Nordic Diet and the Dietary Approaches to Stop Hypertension (DASH diet) are associated with lower risks of diabetes.

Effect of fruit and vegetable intake

DGE 2016 (pdf)
  • 'Increased vegetable intake reduces the risk of type 2 diabetes with probable evidence. This particularly applies to the group of cruciferous vegetables (cabbage etc.)'.
  • '[…] possible evidence [fruit intake] reduces risk for type 2 diabetes mellitus'.

Effect of fibre and whole grain intake

EFSA 2010a
  • 'there is evidence of benefit to health associated with consumption of diets rich in fibre-containing foods at dietary fibre intakes greater than 25 g per day, e.g. reduced risk of coronary heart disease and type 2 diabetes and improved weight maintenance.'
ANSES 2016a (pdf)
  • The consumption of wholegrain cereal products reduces the risk of type 2 diabetes, CVD and colorectal cancer, with a probable level of evidence.
DGE 2016 (pdf)
  • 'There is probable evidence suggesting that a high intake of dietary fibre from cereal grains probably reduces the risk of developing type 2 diabetes mellitus.'
  • '[A]n increased intake of whole grain products was associated with reduced risk particularly of type 2 diabetes.'
SACN 2015 (pdf)
  • 'a diet rich in dietary fibre is associated with a lower incidence of […] type 2 diabetes mellitus […].'
  • 'Higher cereal fibre consumption is associated with a lower incidence of type 2 diabetes mellitus […].'
  • There is moderate evidence that higher consumption of whole grain bread and whole grains is associated with reduced incidence of type 2 diabetes.

Effect of sugars, sweeteners and sugar-sweetened beverages (SSB) intake

ANSES 2016b (pdf)

  • '[… ] sugar consumption beyond a certain quantity presents health risks due to direct effects on weight gain and the increase in triglyceride and uric acid levels, as well as indirect effects on type 2 diabetes and certain cancers, diseases that are currently major public health issues.'
  • There is probable evidence that the risk of type 2 diabetes is increased with higher consumption of sugar-sweetened beverages.
SACN 2015 (pdf)
  • Based on limited evidence, there is 'no consistent evidence of an association between diets differing in the proportion of sugars in relation to incidence of type 2 diabetes mellitus'. Sucrose and fructose were also individually examined, with the same findings.
  • Based on moderate evidence, ‘an association was found between greater sugars-sweetened beverage consumption and higher incidence of type 2 diabetes mellitus.’ ‘The direction of the association indicates that greater consumption of sugars-sweetened beverages is detrimental to health. The association is biologically relevant’. Insufficient evidence for this association was found for fruit juices.
Health Council of the Netherlands 2015
  • 'Consumption of one to two glasses of sugar-containing beverages a day leads to a higher risk of diabetes'
  • those findings are also valid for other sugar-containing beverages, such as fruit juice and sweetened milk drinks
ANSES 2015 (pdf)
  • 'No benefits of intense sweeteners consumption on preventing the occurrence of type 2 diabetes have been demonstrated.'
DGAC 2015
  • 'Strong evidence shows that higher consumption of added sugars, especially sugar-sweetened beverages, increases the risk of type 2 diabetes among adults and this relationship is not fully explained by body weight.'

Effect of protein and protein sources intake on type 2 diabetes

NNR 2012 (pdf)
  • Evidence was assessed as suggestive regarding the relation of total and animal protein intake to increased risk of type 2 diabetes.
ANSES 2016a (pdf)
  • 'The consumption of red meat and processed meats (including delicatessen meats) increases the risk of […] type 2 diabetes, with a "probable" level of evidence'
  • '[T]otal consumption of dairy products (including milk) probably reduces the risk of type 2 diabetes […]. With regard to the types of dairy products, the relationship seems better demonstrated for yoghurts, cheese and reduced-fat dairy products.'

Effect of physical (in)activity and sedentary behaviour on type 2 diabetes risk

WHO 2016 (pdf)
  • Regular physical activity reduces the risk of diabetes and the risk of raised blood glucose
EU Physical Activity Guidelines 2008 (pdf)
  • 'At present there is sufficient evidence to show that those who live a physically active life can gain a number of health benefits, including […] low incidence of type 2 diabetes.'
PAGAC 2018 (pdf)
  • Increased levels of physical activity are associated with lower incidence of type 2 diabetes.
  • 'Strong evidence demonstrates a significant relationship between greater time spent in sedentary behavior and higher risk of type 2 diabetes.' 'Limited evidence suggests the existence of a direct, graded dose-response relationship between sedentary behavior and risk of type 2 diabetes.'

Effect of alcohol consumption on type 2 diabetes risk

WHO 2013 (pdf)
  • 'harmful use of alcohol is one of the key risk factors for the development of NCDs’ (including cardiovascular disease, chronic respiratory disease, cancer, diabetes)
NIAA 2010 (pdf)
  • Heavy drinking can cause different stages of alcoholic liver disease; steatosis (fatty liver), alcoholic hepatitis, liver fibrosis, and cirrhosis. Complications of cirrhosis include jaundice, type 2 diabetes, and liver cancer.
  • Long-term excessive alcohol consumption can cause chronic pancreatitis, which is a risk factor for the development of diabetes and pancreatic cancer.
Health Council of the Netherlands 2015
  • 'the findings regarding moderate alcohol consumption include both favourable and unfavourable associations between alcohol consumption and chronic diseases risk [including diabetes], while higher consumption levels are associated with higher risks of chronic diseases.'
  • 'People who drink alcohol should limit themselves to one glass a day. The distribution of alcohol consumption is also important: although one glass a day is acceptable, an average of one glass a day resulting from occasional or regular binge drinking is undesirable.'

Effect of smoking on type 2 diabetes risk

WHO 2016 (pdf)
  • Emerging evidence [exists] of a link between smoking and type 2 diabetes risk. Smoking increases the risk of type 2 diabetes, as well as the risk of diabetes-related complications
CDC 2014 (pdf)
  • 'The evidence is sufficient to infer that cigarette smoking is a cause of diabetes.'
  • 'The risk of developing diabetes is 30–40% higher for active smokers than nonsmokers.'
  • 'There is a positive dose-response relationship between the number of cigarettes smoked and the risk of developing diabetes.'